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Lumacaftor; Ivacaftor: (Minor) Concomitant use of diphenhydramine and lumacaftor; ivacaftor could alter diphenhydramine exposure; monitor for diphenhydramine efficacy and opposed occasions. Lumateperone: (Moderate) Monitor for excessive sedation and somnolence throughout coadministration of lumateperone and diphenhydramine. Maprotiline: (Moderate) Additive anticholinergic results could also be seen when maprotiline is used concomitantly with different generally used medicine with average to important anticholinergic results, corresponding to diphenhydramine, a sedating H1-blocker. Meperidine: (Moderate) Concomitant use of opioid agonists with diphenhydramine could cause excessive sedation and somnolence. Metformin; Pioglitazone: (Moderate) Sympathomimetic agents and adrenergic agonists are inclined to increase blood glucose concentrations when administered systemically. Methadone: (Moderate) Concomitant use of opioid agonists with diphenhydramine could cause excessive sedation and somnolence. Methyclothiazide: (Moderate) The cardiovascular results of sympathomimetics could scale back the antihypertensive results produced by diuretics. Methyldopa: (Major) Sympathomimetics, corresponding to phenylephrine, can antagonize the antihypertensive results of methyldopa when administered concomitantly. Blood stress ought to be monitored closely to verify that the desired antihypertensive impact is achieved. Methylphenidate: (Moderate) Methylphenidate can potentiate the actions of each exogenous (corresponding to dopamine and epinephrine) and endogenous (corresponding to norepinephrine) vasopressors. It is advisable to monitor cardiac perform if these medications are coadministered. Vasopressors embrace medications corresponding to epinephrine, dopamine, midodrine, and non-prescription medications corresponding to pseudoephedrine and phenylephrine. Metolazone: (Moderate) The cardiovascular results of sympathomimetics could scale back the antihypertensive results produced by diuretics. Coadministration of midodrine with different vasoconstrictive agents, corresponding to phenylephrine, could enhance or potentiate the consequences of midodrine. Advise against driving or engaging in different actions requiring mental alertness until patients know how this mixture impacts them. Naproxen; Pseudoephedrine: (Major) Pseudoephedrine can potentiate the consequences and increase the toxicity of different sympathomimetics by adding to their sympathomimetic exercise. Nebivolol: (Moderate) Monitor for increased toxicity as well as increased therapeutic impact of nebivolol if coadministered with diphenhydramine. If these medicine are administered concurrently, monitor for diphenydramine toxicity, corresponding to drowsiness, or decreased effectiveness. Oxycodone: (Moderate) Concomitant use of opioid agonists with diphenhydramine could cause excessive sedation and somnolence. Oxymorphone: (Moderate) Concomitant use of opioid agonists with diphenhydramine could cause excessive sedation and somnolence. Oxytocin: (Major) The administration of prophylactic vasopressors with oxytocin may cause severe, persistent hypertension, as the two medicine could have a synergistic and additive vasoconstrictive impact. Perphenazine; Amitriptyline: (Moderate) Additive anticholinergic and sedative results could also be seen when perphenazine is used with first era antihistamines, corresponding to diphenhydramine. All sympathomimetics and psychostimulants, including different anorexiants, ought to be used cautiously or prevented in patients receiving phendimetrazine. The mixed use of these agents could have the potential for additive side effects, corresponding to hypertensive crisis or cardiac arrhythmia. Many nonprescription products for coughs, colds, allergy, hay fever, or insomnia include sedating antihistamines. Phenothiazines: (Moderate) Other non-cardiovascular medicine with alpha-blocking exercise corresponding to phenothiazines, directly counteract the consequences of phenylephrine and may counter the desired pharmacologic impact. Phenoxybenzamine: (Major) Sympathomimetics can antagonize the consequences of antihypertensives corresponding to alpha-blockers when administered concomitantly. Phentermine: (Major) Because phentermine is a sympathomimetic and anorexic agent (i.
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Nonprescription medicines, vitamins, natural remedies, and sure foods can also work together. List all the prescription medicines, nonprescription medicines, dietary supplements, natural remedies, and vitamins that you simply take. Ask your healthcare supplier or pharmacist for more data or in case you have any questions. Last modified: 2014-11-26Last reviewed: 2014-11-24 This content is reviewed periodically and is subject to change as new health data becomes out there. There are a number of issues that may contribute to a lower in appetite, together with developmental stages or medical conditions. Thiamine A deficiency of thiamine, also referred to as vitamin B-1, can cause: increased resting energy expenditure, or the rate you burn energy when restingdecreased appetiteweight lossThiamine should be protected for many adults. These drugs are:Dronabinol (Marinol) Dronabinol is a cannabinoid medicine. It stimulates appetite and promotes weight achieve similarly to anabolic steroids or naturally occurring testosterone in the body. These drugs include: There are a number of methods to assist increase your appetite besides taking drugs or dietary supplements. Daily calorie necessities range based mostly on a number of elements, similar to: sexactivity levelgenetic makeupresting metabolismbody typeBelow is a basic guideline for average calorie necessities by age group. If left untreated, low appetite can lead to malnourishment and different critical health points. It�s possible to increase appetite with appetite stimulant drugs, dietary supplements, and life-style modifications. As the mast cells destroy the allergens, a chemical called histamine is launched into the bloodstream. A great amount of histamine swells body tissues (irritation), causes itching, enlarges blood vessels, increases secretions, and causes bronchospasm (tightening of muscles that encompass the airways). Treatment options include over-the-counter and prescription antihistamines, anti-leukotrienes, nasal steroids, and nasal cromolyn. To assist handle mud mite allergies, strive using mud mite encasements (airtight plastic/polyurethane covers) over pillows, mattresses, and box springs. Molds Molds are parasitic, tiny fungi (like Penicillium) with spores that float in the air like pollen. Other allergens include: Latex Some individuals can develop a latex allergy after repeated contact with latex. Skin rash, hives, eye tearing and irritation, wheezing, and itching of the skin could happen in individuals with latex allergy. More severe reactions can happen if the mucosal membranes are exposed, similar to throughout an operation or a dental or gynecologic examination. Symptoms of food allergy include itching, hives, nausea, vomiting, diarrhea, respiratory difficulties, and swelling around the mouth. If you (or your child) have a food allergy, your doctor could prescribe injectable epinephrine (adrenaline) so that you can carry at all times. Do not pull on the stinger, as it will cause the release of more venom into the skin. Symptoms of an allergic reaction to an insect sting include: Difficulty respiratory. More than 50 million Americans (1 in 6) suffer from all types of allergies, together with indoor/outside allergies, food and drug, latex, insect, skin and eye allergies. You ought to nonetheless keep your reliever inhaler with you at all times in case you do have an bronchial asthma assault. Seretide accuhaler and evohaler each include two active elements, a corticosteroid called fluticasone propionate and a bronchodilator called salmeterol xinafoate. Fluticasone is a person-made derivative of the natural hormones and is used to lower irritation in the lungs. It stops these cells from releasing chemical substances that normally cause immune and allergic responses resulting in irritation.
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In some instances, an individual might have blood tests or further observation in a hospital. In some instances, docs may give an individual activated charcoal, which helps prevent the absorption of some drugs and chemical substances in the intestine. Antihistamines could also be first technology (sedating) or second technology (nonsedating). Second technology antihistamines are newer medicine and are less more likely to have these results. First technology antihistamines obtainable over-the-counter include:diphenhydramine (Benadryl) chlorpheniramine (Chlor-Trimeton)brompheniramine (Dimetapp)clemastine (Tavist)doxylamine (Unisom)hydroxyzine (Vistaril)promethazine (Promethegan)triprolidine (Actidil)These drugs can act as sedatives, to allow them to make an individual feel tired or dizzy. Some specialists say first technology antihistamines are more likely to result in demise from accidents or overdoses than their second technology counterparts. Second and third technology antihistamines obtainable over-the-counter include:cetirizine (Zyrtec)fexofenadine (Allegra)loratadine (Claritin)These newer antihistamines are less more likely to trigger drowsiness and dizziness. Research has found them less more likely to trigger dangerous results if an individual takes too much. Some antihistamines are protected for children to take, but it is very important ask a doctor or pharmacist about the proper dose. Weight gain tablets include over-the-counter supplements and drugs prescribed by a doctor. Your provider would possibly think about steroid medicine if you have experienced vital weight reduction and are underweight as the result of an sickness, similar to most cancers or muscular dystrophy. Inappropriate use of anabolic steroids comes with health dangers�a few of that are severe. Like many different supplements, these products are usually packaged and marketed with overstated guarantees and guarantees. If a weight gain capsule or supplement makes claims that appear too good to be true, they probably are. People with coronary heart situations could be at an elevated risk for an irregular heartbeat. If you need to gain weight, there are more healthy, safer, proof-backed methods to do so, similar to including extra calorie-dense meals to your food regimen. Working with a registered dietitian may give you personalized recommendations for what your physique needs to gain weight in a protected, wholesome means. Consumer Medicine Information What is on this leaflet This leaflet solutions some frequent questions on Asmol inhaler. This medicine is only part of a common plan to assist you to handle your asthma or different chest situations. What Asmol inhaler is used for Asmol inhaler is used to help deal with the signs of: different respiratory problems. In individuals who have issue respiratory throughout exercise, Asmol inhaler may also be used earlier than exercise to hold the air passages open. Salbutamol belongs to a bunch of medicines called bronchodilators or beta-2 agonists. Asmol inhaler gives fast reduction out of your chest signs and is usually called a "reliever" medicine. Some individuals start wheezing or their chest begins to feel tight once they exercise. Ask your physician if you have any questions on why Asmol inhaler has been prescribed for you. Some of the signs of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may trigger issue in swallowing or respiratory, wheezing or shortness of breath. Do not use this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. The ingredients of Asmol inhaler are identified to cross the placenta throughout pregnancy. Your physician will talk about the dangers and advantages of using Asmol inhaler throughout pregnancy.
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Statistical evaluation Measured prednisolone concentrations had been plotted against time to produce prednisolone day curves. This end result was concordant with the expected prednisolone concentration at 14 h, calculated by extrapolating the terminal half-life decided from previous data points and preliminary day curves in a number of individuals, which demonstrated full clearance by 14 h. No important carryover was detected between injected samples containing high concentrations of prednisolone and injected samples containing low concentrations of prednisolone. Eleven day curves had been performed on single day by day prednisolone dosing and had been available for pharmacokinetic evaluation. The terminal half-lifetime of prednisolone was conserved in individuals who had more than 1 day profile, despite the variations in the administered dose. The mixture of increased receptor binding affinity and the discrete pharmacokinetic profile of prednisolone with the longer half-life than hydrocortisone would both contribute to an increased dose ratio when in comparison with hydrocortisone. It is, nevertheless, the perception that prednisolone confers a higher danger of antagonistic metabolic results that has confirmed the largest impediment to its widespread use. It is important that sufferers realize the impression of adjusting the timing of their doses. This methodology permits correct day curve monitoring and dose titration in sufferers with adrenal insufficiency on prednisolone. Prednisolone is superior to the present normal of thrice-day by day hydrocortisone at mimicking the physiological cortisol profile and, with a once-day by day administration, may promote higher compliance. Together with our data, this means that a dose of between 3 and 5 mg prednisolone once day by day is prone to be enough glucocorticoid replacement for many sufferers. Increased death danger and altered most cancers incidence pattern in sufferers with isolated or mixed autoimmune major adrenocortical insufficiency. Improving glucocorticoid replacement therapy using a novel modified-launch hydrocortisone tablet: a pharmacokinetic examine. Treatment of congenital virilizing adrenal hyperplasia sufferers with single and multiple day by day doses of prednisone. Daily cortisol manufacturing fee in man decided by secure isotope dilution/mass spectrometry. Development and validation of a quantitative assay based mostly on tandem mass spectrometry. Binding of steroids to mineralocorticoid receptors: implications for in vivo occupancy by glucocorticoids. Pharmacokinetics of complete and unbound prednisone and prednisolone in secure kidney transplant recipients with diabetes mellitus. The influence of hydrocortisone substitution on the standard of life and parameters of bone metabolism in sufferers with secondary hypocortisolism. Uncontrolled asthma in these taking by inhaled corticosteroids and lengthy-acting bronchodilators. It is further really helpful that quick course, or "burst" therapy, be continued until a baby achieves a peak expiratory flow fee of eighty% of his or her private finest or symptoms resolve. PharmacodynamicsAnti-inflammatory motion: Prednisolone stimulates the synthesis of enzymes needed to lower the inflammatory response. It suppresses the immune system by decreasing exercise and volume of the lymphatic system, thus producing lymphocytopenia (primarily of T-lymphocytes), reducing immunoglobulin and complement ranges, reducing passage of immune complexes via basement membranes, and presumably by depressing reactivity of tissue to antigen-antibody interactions. The mineralocorticoids regulate electrolyte homeostasis by acting renally at the distal tubules to improve the reabsorption of sodium ions (and thus water) from the tubular fluid into the plasma and improve the excretion of both potassium and hydrogen ions. Acetate and tebutate suspensions for injection have a variable absorption fee over 24 to 48 hours, depending on whether or not injected into intra-articular area or muscle, and on blood provide to that muscle. Distribution: Removed rapidly from blood and distributed to muscle, liver, skin, intestines, and kidneys. Extensively sure to plasma proteins (transcortin and albumin); solely unbound portion is lively. Excretion: Inactive metabolites, and small quantities of unmetabolized drug, excreted in urine.
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So if he starts consuming 3000 energy a day, persistently, he ought to start seeing weight achieve. These medicines are inhaled by way of your mouth so they can instantly reach your lungs. As such, combining medicines requires careful planning and medical recommendation to avoid potentially dangerous side effects. All of these actions might help cut back airway constriction so that air can move into your lungs extra successfully as you breathe. Symptoms: Symptoms of both shortness of breath (dyspnea) or exercise intolerance are very important in selecting treatment. It is a mixture of fluticasone, a corticosteroid, and salmeterol, a long-appearing bronchodilator. Each model of this medicine is available in a package deal with directions to be used, as the doses are barely different. Bevespi Aerosphere Bevespi Aerosphere is a mixture of two lengthy-appearing bronchodilators, glycopyrrolate and formoterol. It is taken as two inhalations twice per day, every supplying 9 mcg glycopyrrolate and four. The medicine is available in two double-foil blister strips of powder formulation for oral inhalation. Side Effects Side effects include higher respiratory infections, complications, and fungal mouth an infection. Side Effects Side effects include chest pain and back pain, diarrhea, sinusitis, leg cramps, shortness of breath, rash, flu, leg swelling, and lung disease. The resolution is used with a standard jet nebulizer with a facemask or mouthpiece connected to an air compressor. This medicine is available as an inhaled powder in doses of ninety mcg and 180 mcg or a nebulized suspension at doses of zero. It can also be out there in an 18 mcg powder-stuffed capsule to be used with a HandiHaler device, which can also be taken as two inhalations once per day. It is available in a tool containing dry powder metering and used to ship four hundred mcg aclidinium bromide per inhalation. It is provided in both a 15 g pressurized canister containing 200 doses or an 8. The lively ingredient in Rhinocort nasal spray is budesonide, which is a corticosteroid that helps forestall the discharge of chemical compounds that cause irritation in the physique. More Common Rhinocort Side Effects Bloody nose Dry or sore throat Fever Cough Difficulty swallowing Tightness in chest In rare cases, Rhinocort could cause a severe allergic response. Most individuals begin with one spray per nostril and improve it to two if they want a better dose. After spraying, take away the applicator tip from your nostril and tilt your head back for several seconds for the spray to reach the back of your nose. It helps cut back irritation in the physique which may forestall symptoms like a runny nose, itchy eyes, and congestion. Rhinocort is mostly safe to use, but it could have side effects corresponding to a bloody nose, sore throat, and fever. To take Rhinocort, insert the applicator into one nostril, spray it one to two times, and repeat with the opposite nostril. Have regular checkups with your physician or to make sure you are getting the proper medicines. Learning about what triggers your asthma, the early warning signs to search for and the way to use your medicine the proper means will allow you to keep your asthma under management. This mucus could be very thick and sticky, and should kind into plugs which will utterly block a few of the airways. When the airways swell, these muscle bands typically constrict or clamp down, further narrowing or squeezing the airways. Together, airway swelling, excess mucus, and tightened muscle bands cause airway narrowing and make it hard to breathe. Your lengthy-time period controller medicine is the one which works over a long period of time to help keep the irritation in your airways down, and cease them from being so twitchy.
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A gentle and uncomfortable tightening of the throat in addition to blotchy face can also be a typical symptom. Sicherer nbsp 17 Aug 2020 I found out later that seafood corresponding to shrimp and other shellfish combined with onerous liquors will create a poison in your physique causing opposed nbsp 10 Jun 2011 The approximate prevalence of shellfish allergy is estimated at zero. Yeast is the nbsp 10 Sep 2020 Seafood proteins Sodium metabisulfite Sulfites Wheat Yeast. Unfortunately the only confirmed method to deal with seafood and shellfish allergy symptoms is to avoid them utterly. May 19 2016 The most extreme allergic response to sulfites which could be life threatening is anaphylactic shock. Any one of those might trigger an allergic like response and can also be found Peanuts nuts f ish and shellfish usually trigger meals allergy symptoms in adolescents and adults. Jan 04 2019 The most common meals people are allergic to embody cow s milk peanuts tree nuts soy fish shellfish and wheat. Jun 10 2011 The reputation of shellfish has been rising worldwide with a consequent enhance in opposed reactions that can be allergic or poisonous. Food associated reactions are related to a broad array of indicators and signs that will involve many bodily techniques including the pores and skin gastrointestinal and respiratory tracts and cardiovascular system. Foods accountable for the majority of all allergic reactions embody milk wheat eggs peanuts tree nuts soy fish and shellfish. What most individuals believe to be alcohol allergy is actually a response to an allergen current in the alcoholic beverage like barley hops yeast rye wheat gluten histamines usually found in red wine and sulfites usually found in white wines. Sep 22 2020 Consulting 911 could be helpful in suspected cases of a extreme allergic response. The Mayo Clinic defines contact dermatitis as a red itchy rash attributable to direct contact with a substance or an allergic Comprehensive alcohol amp meals interactions for lisinopril. People who react to one type of shellfish nbsp eight Mar 2019 Drinking with meals allergy symptoms is sophisticated. Shellfish could cause extreme and probably life threatening allergic reactions corresponding to anaphylaxis. Symptoms of meals allergy embody Jan 01 2010 Sulfur dioxide is of course produced through the manufacturing of wine and might trigger allergic reactions when folks drink wine the consultants say. Jan 31 2020 Food allergy symptoms have gotten more and more common with roughly eight of children and 5 of adults affected by a minimum of one meals allergy. Most meals have the potential of causing allergy symptoms however a few are extra probably and shellfish are among the many eight Sep 01 1985 The solely allergens up to now identified in Crustacea have been warmth steady and heat labile al lergens current in shrimp studied by Hoffman et ai. The immune system usually protects the physique from dangerous agents corresponding to micro organism and toxins. Doctors give unbiased helpful info on indications contra indications benefits and complications Dr. Dust is an incredibly common gentle allergy as is pollen and many several types of meals. Among nbsp by consultants on allergy symptoms on meals allergy and cross contamination with drinks. But as the bulk of people who demonstrate an allergic response to one sort of shellfish normally are allergic to other varieties specialist allergists normally advise their sufferers to avoid all varieties. Comparing alcohol to an allergen might assist some folks understand that dependancy is a disease and never a choice. The manifestations of shellfish allergy differ broadly nevertheless it tends to be extra extreme than Obedience to these laws means abstinence from pork shellfish and other animals proscribed as quot unclean quot. An allergic response normally happens inside minutes after being uncovered to an allergen however sometimes it could possibly take place a number of hours after exposure. Nov 26 2019 Alcohol primarily based hand cleansers might trigger burning and stinging however that is normally because of the pores and skin already being damaged and irritated. Sep 14 2019 Anaphylaxis is a extreme probably life threatening allergic response. Nov 03 2011 quot Alcohol is actually at the very top of the record of meals components that have an effect on the most individuals with migraine quot says Dr. It is characterized by incapability to breathe because of swelling adopted by wheezing coughing and choking with other signs like low blood pressure weak spot pale pores and skin blue lips and fainting. Food allergy is a number one cause of anaphylaxis and due to this fact referral to an allergist for acceptable and May 30 2014 The chance of allergic reactions attributed to traces of chitosan used as a fining agent in wine has not been ruled out significantly in shrimp allergic sufferers to whom small traces of the potential allergen may be sufficient to trigger anaphylactic reactions.
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Ask your physician or pharmacist to show you the correct method of applying eye drops. It is essential to avoid touching the dropper tip to any surface, skin, or your eye. If you miss a dose, instill it as quickly as possible and continue with your common schedule. Store this medicine at room temperature, protect it from mild and moisture and keep it out of the reach of youngsters. Do not use prednisolone acetate eye drops if you: are allergic to prednisolone or any ingredients of the medicine have had an allergic or sensitivity response to other corticosteroids have acute herpes simplex, tuberculosis of the attention, vaccinia, chickenpox, or other viral or fungal diseases of the attention have any eye an infection associated with discharge have conjunctivitis or blepharitis associated with discharge have recently had a foreign body removed from the attention What unwanted side effects are possible with this medicine? Check with your physician as quickly as possible if any of the following unwanted side effects occur: difficulty focusing eye ache skin rash, itching, redness, or swelling in or across the eyes vision adjustments Some individuals might expertise unwanted side effects other than these listed. Contact lenses: Using contact lenses with corticosteroid eye drops increases the danger of an infection. It is advisable to avoid carrying contact lenses whereas using corticosteroid eye drops. Glaucoma: The use of corticosteroids within the eyes might trigger an increase within the pressure within the eye. Infection: Corticosteroids corresponding to prednisolone acetate reduce signs of inflammation by lowering the effect of the immune system. As a end result, the use of this medicine might cover the indicators of new infections or worsening of present infections. If you notice any new eye signs corresponding to ache, redness, sensitivity to daylight or vision adjustments, contact your physician immediately. Pregnancy: Very little prednisolone acetate in an eye fixed drop type is absorbed into the body and available to affect an unborn child. For this purpose, prednisolone acetate eye drops are thought-about secure to use throughout being pregnant for brief periods of time. Breast-feeding: Corticosteroids cross into breast milk, nonetheless in an eye fixed drop type, little or no prednisolone acetate is absorbed into the body and available to cross into breast milk. The use of corticosteroid eye drops, including prednisolone acetate, is taken into account to be secure whereas breast-feeding. Since caffeine, alcohol, the nicotine from cigarettes, or road medication can affect the motion of many drugs, you need to let your prescriber know if you use them. More than half of these pediatric sufferers expertise an asthma exacerbation each year. Prednisolone, a liquid formulation of prednisone, is often prescribed to these youngsters as a result of its ease of administration. Poor adherence as a result of the bitterness or laxative qualities of prednisolone usually limits its effectiveness, nonetheless, and cautious selection should be made between the available varieties (prednisolone base versus prednisolone sodium phosphate). Treatment After choosing up the prednisolone from the pharmacy, the mom gives her youngster the prescribed dose of 5 mL. There they uncover that the mistaken formulation of prednisolone was distributed, which was most likely liable for the failure of home therapy. The physician had prescribed the generic for Orapred solution (prednisolone sodium phosphate), however the pharmacist had distributed the bitter-tasting prednisolone base (generic for Prelone). Corticosteroids and Asthma Systemic corticosteroids are an essential remedy possibility for many disease states, particularly asthma. The most common adverse effects are the same for the majority of oral corticosteroids and embody increased urge for food, weight achieve, flushed face, and increased zits in adolescents. Considering that the final quantity of prednisolone provided by every formulation is consistent, it would be anticipated that these adverse effects can be comparable for all. Diminished adherence might be as a result of the type of prednisolone distributed to the affected person. There is, nonetheless, a notable distinction between prednisolone sodium phosphate (an ester) and prednisolone base. Sorbitol, a sugar alcohol, is used to increase the palatability of prednisolone sodium phosphate. Considering the benefits of short bursts of systemic corticosteroid therapy, it is important to make sure that sufferers tolerate the drug prescribed. Prednisolone sodium phosphate should be preferentially chosen over prednisone base when prescribing liquid forms of oral corticosteroids.